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deacethyl asperulosidic acid

Deacetyl asperulosidic acid

CAS: 14259-55-3

Molecular Formula: C16H22O11

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deacethyl asperulosidic acid - Names and Identifiers

Name Deacetyl asperulosidic acid
Synonyms Deacetyl asperulosidic acid
Desacetyl asperulosidic acid
deacethyl asperulosidic acid
Asperulosidic Acid Impurity 2 (Desacetylasperulosidic Acid)
(1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
(1S,4aS,5S,7aS)-1-(b-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid
(1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-(hydroxymet hyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
Cyclopenta[c]pyran-4-carboxylicacid, 1-(b-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)-,(1S,4aS,5S,7aS)-
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)-, (1S,4aS,5S,7aS)-
CAS 14259-55-3

deacethyl asperulosidic acid - Physico-chemical Properties

Molecular FormulaC16H22O11
Molar Mass390.34
Density1.73
Boling Point744.1±60.0 °C(Predicted)
Specific Rotation(α)(c, 1.7 in MeOH)+26
Solubility Soluble in water, alkaline solution, insoluble in petroleum ether.
AppearanceWhite powder
pKa4.34±0.70(Predicted)
Storage Condition2-8℃
MDLMFCD21364062
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, ethyl acetate, almost insoluble in water, from the pig, Morinda officinalis, Hedyotis diffusa.

deacethyl asperulosidic acid - Reference

Reference
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1. Shen Yu, he Yuqiong, Zhang Qi, Liu mengqin, Xinhai, Zhang Quan-long, Qin Lu-ping, Zhang Qiaoyan. Preparation of iridoid glycosides from Morinda officinalis how and their inhibitory effect on bone resorption of osteoclasts [J]. Academic Journal of Second Military Medical University, 2019,40(02):149-156.
2. Shi Yuehua, Yan Qiuying, fan Huisen et al. Simultaneous determination of three diterpenoids in rat plasma by UHPLC-MS/MS after intragastric administration of hedyotis diffusa aqueous extract and its pharmacokinetics [J]. Journal of Pharmaceutical Analysis, 2019, 039(005):813-820.
3. He, Jingyu, et al. "Asperuloside and asperulosidic acid entert an anti-ignition effect via inhibition of the NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages." International journal of molecular sciences 19.7 (2018): 2027.https://
4. [IF = 4.183] Jingyu He et al."Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages."Int J Mol Sci. 2018 Jul;19(7):2027
5. [IF=3.659] Shen Yi et al."Pharmacokinetics and tissue distribution of monotropein and deacetyl asperulosidic acid after oral administration of extracts from Morinda officinalis root in rats."Bmc Complem Altern M. 2018 Dec;18(1):1-12
6. [IF=5.878] Li DanQing et al."N-butanol extract of Hedyotis diffusa protects transgenic Caenorhabditis elegans from Aβ-induced toxicity."Phytother Res. 2021 Feb;35(2):1048-1061
7. [IF=5.34] Wei Zou et al."Imperatae rhizoma-Hedyotis diffusa Willd. herbal pair alleviates nephrotic syndrome by integrating anti-inflammatory and hypolipidaemic effects."Phytomedicine. 2021 Sep;90:153644
8. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9
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